Publications
Selected landmark and recent work
Explore work on wild-type and mutant p53, DNA-damage checkpoints, transcriptional control and cancer biology.
Mutant p53: evolving perspectives
Genes & Development
Mutant p53 regulates a distinct gene set by a mode of genome occupancy that is shared with wild type
EMBO Reports
In vivo RNA-seq and ChIP-seq analyses show an odd-skipped related 2 transcriptional regulatory network in osteoblasts
Journal of Bone and Mineral Research
p53 Frameshift Mutations Couple Loss-of-Function with Unique Neomorphic Activities
Molecular Cancer Research
Distinct mechanisms control genome recognition by p53 at its target genes linked to different cell fates
Nature Communications
Mdm2 and MdmX: Partners in p53 Destruction
Cancer Research
Inactivation of Wild-Type p53 by Asparagine Endopeptidase in Glioblastoma
Journal of the National Cancer Institute
Tumor suppression by p53 involves inhibiting an enabler, FGF13
Proceedings of the National Academy of Sciences
p53-independent effects of Mdm2
Sub-Cellular Biochemistry
Life or death decisions by the tumour suppressor p53
EMBO Reports
Mdm2 swings both ways as an oncogene and a tumor suppressor
Genes & Cancer
Gene-specific mechanisms of p53 transcriptional control and prospectus
FEBS Letters